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PLLA Collagen Boosting Injection 童颜针/ 舒颜萃

What is PLLA Collagen Boosting Injection?

PLLA Collagen Boosting Injection, is a collagen biostimulator approved by the US FDA since 2004. After injection, PLLA Collagen Boosting Injection stimulates skin cells to produce new collagen and elastin- this improves skin quality and results in firmer, lifted skin with less fine lines and sagging1,2. Common treatment areas include the temple, cheeks, nasolabial fold and chin.

How does PLLA Collagen Boosting Injection work?

Each vial of PLLA Collagen Boosting Injection contains Poly-L-Lactic Acid (PLLA) 150mg, Sodium carboxymethycellulose (CMC) 90mg and mannitol 127mg. PLLA Collagen Boosting Injection, when injected into the dermis or subcutaneous tissue of the treatment area, triggers a controlled inflammatory effect and stimulates skin cells known as fibroblasts to produce collagen and elastin to improve the skin’s structural integrity and elasticity.
Over time, PLLA is absorbed by the body and the newly formed collagen and elastin remains, thus creating natural and subtle-looking results. Clinical studies have shown that the level of Type 1 Collagen increases by 66.5% after a PLLA Collagen Boosting Injection treatment.

Why choose PLLA Collagen Boosting Injection?

PLLA Collagen Boosting Injection is ideal for clients who are seeking rejuvenation but wish for a more subtle and natural look. As compared to hyaluronic acid fillers where “what you see is what you get”, the results from PLLA Collagen Boosting Injection occur gradually over 1-3 months and can last up to 24 months. While PLLA Collagen Boosting Injection costs more than a hyaluronic acid filler, it may be more cost effective given the long-lasting effects.
  • Long-lasting and natural-looking results
  • No downtime, minimally invasive treatment
  • Safe with over 20 years of clinical use

What conditions can PLLA Collagen Boosting Injection treat?

  • Facial volume loss: PLLA Collagen Boosting Injection addresses age related treatment facial volume loss
  • Nasolabial folds and marionette lines: by replenishing volume and tightening skin, PLLA Collagen Boosting Injection improves the appearance of the deep folds of the face
  • Skin laxity: PLLA Collagen Boosting Injection improves skin firmness and reduces sagging
  • Jawline definition: PLLA Collagen Boosting Injection improves contours of the jawline

What can I expect from PLLA Collagen Boosting Injection treatment?

The doctors at Bay Aesthetics Clinic will evaluate your skin, discuss your aesthetic goals, and recommend a personalised treatment plan. After anaesthesia has been applied, PLLA Collagen Boosting Injection is injected via a cannula.

After treatment, patients experience mild swelling at the injection sites for 2-3 days.

How many PLLA Collagen Boosting Injection sessions are required?

The guideline is 1 vial of PLLA Collagen Boosting Injection per decade of age. For each PLLA Collagen Boosting Injection session, 2 vials of PLLA Collagen Boosting Injection is injected for full face rejuvenation. PLLA Collagen Boosting Injection treatments are spaced 4-6 weeks apart. Once a good result has been achieved, maintenance treatments are recommended every 12-18 months.

Client in 30-40s, early signs of ageing

total 4 vials of PLLA Collagen Boosting Injection sessions, 2 vials of PLLA Collagen Boosting Injection per treatment

Client in 50-60s, moderate signs of ageing (ie skin sagging)

total of 6 vials of PLLA Collagen Boosting Injection: 3 PLLA Collagen Boosting Injection sessions, 2 vials of PLLA Collagen Boosting Injection per treatment-

Body area:

Abdomen: 6-8 vials of PLLA Collagen Boosting Injection

Buttocks: 6-8 vials of PLLA Collagen Boosting Injection

Arms: 3-4 vials of PLLA Collagen Boosting Injection

Who is PLLA Collagen Boosting Injection suitable for?

PLLA Collagen Boosting Injection is recommended for patients with signs of facial ageing such as fine lines, sagging skin and volume loss.

PLLA Collagen Boosting Injection has also been used to treat loose skin on the body such as the abdomen, buttocks or arms.

PLLA Collagen Boosting Injection is not recommended for patients who are pregnant, breastfeeding or a history of keloid scarring.

Is PLLA Collagen Boosting Injection safe?

The key ingredient of PLLA Collagen Boosting Injection, is broken down by the skin into carbon dioxide and water. PLLA Collagen Boosting Injection is approved by the US FDA, Europe’s CE Mark, Korean FDA, Singapore’s HSA. PLLA Collagen Boosting Injection has been approved for cosmetic use for over 20 years, the ingredient PLLA has been used for medical purposes for over four decades.

Risks of PLLA Collagen Boosting Injection

Patients may experience bruising, swelling or mild discomfort after PLLA Collagen Boosting Injection, which resolves after 2-3 days.

Rare but serious side effects include: vascular occlusion, infection, nodules and granulomas

An experienced PLLA Collagen Boosting Injection doctor will know how to avoid complications and address serious side effects should they arise

PLLA Collagen Boosting Injection should NOT be used to treat the forehead, eye area, nose or lips due to the high incidence of nodule formation.

PLLA Collagen Boosting Injection vs HA filler vs Ellanse vs Radiesse?

PLLA Collagen Boosting Injection

Main component

PLLA (Poly-L-Lactic Acid)

Mechanism of action

Delayed new collagen production, minimal volume restoration

Duration of results

24 months

Volume required

4-6 vials (10ml per vial) for full face rejuvenation

Treatment areas

Face, body

Cost

$1000-1500 per vial (10ml)

PCL collagen boosting injection

Main component

Polycaprolactone (PCL) microspheres in CMC gel carrier

Mechanism of action

Immediate volume restoration with delayed new collagen production

Duration of results

Ellanse S- 18 months
Ellanse M- 2 years

Volume required

4-8 syringes (1ml per syringe) for full face rejuvenation

Treatment areas

Face only

Cost

$1000-1500 per syringe (1ml)

HA filler

Main component

Hyaluronic acid (HA), crosslinked

Mechanism of action

Immediate volume restoration, no collagen production

Duration of results

Lasts 9 to 12 months, depends on brand and product

Volume required

4-8 syringes (1ml per syringe) for full face rejuvenation

Treatment areas

Face only

Cost

$600-1000 per syringe (1ml)

CaHA collagen boosting injection

Main component

Calcium hydroxyapatite (CaOH) in CMC Gel carrier

Mechanism of action

Immediate volume restoration with delayed new collagen production

Duration of results

12-18 months

Volume required

4-6 syringes (1.5ml per syringe) for full face rejuvenation

Treatment areas

Face and hands

Cost

$1500-1800 per syringe (1.5ml)
 

Ellanse

A syringe and box

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Hyaluronic acid dermal filler (eg Juvederm, Belotero, Restylane)

A box of medicine with a logo

Description automatically generated

Sculptra

A box of a product

Description automatically generated with medium confidence

Radiesse

A syringe and a box

Description automatically generated

Main component Polycaprolactone (PCL) microspheres in CMC gel carrier Hyaluronic acid (HA), crosslinked PLLA (Poly-L-Lactic Acid)  Calcium hydroxyapatite (CaOH) in CMC Gel carrier
Mechanism of action Immediate volume restoration with delayed new collagen production Immediate volume restoration, no collagen production Delayed new collagen production, minimal volume restoration Immediate volume restoration with delayed new collagen production
Duration of results Ellanse S- 18 monthsEllanse M- 2 years Lasts 9 to 12 months, depends on brand and product 24 months 12-18 months
Volume required 4-8 syringes (1ml per syringe) for full face rejuvenation 4-8 syringes (1ml per syringe) for full face rejuvenation 4-6 vials (10ml per vial) for full face rejuvenation 4-6 syringes (1.5ml per syringe) for full face rejuvenation
Treatment areas Face only Face only Face, body Face and hands
Cost ~$1000-1500 per syringe (1ml) ~$600-1000 per syringe (1ml) $1000-1500 per vial (10ml) $1500-1800 per syringe (1.5ml)

PLLA Collagen Boosting Injection in Singapore

PLLA Collagen Boosting Injection is a registered medical device (implant) in Singapore and needs to be injected by a medical professional with advanced postgraduate training. PLLA Collagen Boosting Injection needs to be injected by an aesthetic doctor (with a Certificate of Competency for filler injection), plastic surgeon or dermatologist. In addition, the doctor should have completed advanced live injection training in PLLA Collagen Boosting Injection and also perform a high volume of PLLA Collagen Boosting Injection cases regularly.

Price of PLLA Collagen Boosting Injection in Singapore

PLLA Collagen Boosting Injection costs $1000-1500 per vial, depending on clinic location and treatment package. 

 

Price of PLLA Collagen Boosting Injection at Bay Aesthetics Clinic

First time treatment- $988 nett per vial

Ala carte 1 vial- $1200 + GST per vial

Package of 4 vials- $1100 + GST per vial

Package of 8 vials- $1000 + GST per vial

With over 10 years of experience in aesthetic treatments, Dr Hoe Ying Min serves as the Medical Director at Bay Aesthetics Clinic. She has extensive hands-on experience in lasers, injectables, body-shaping and skin-rejuvenation procedures, and is known for her careful, personalised approach that aims for natural-looking outcomes.

Bay Aesthetics Clinic and Medispa is a doctor-led clinic located in the Marina Bay Financial Centre that delivers medical aesthetics and medispa treatments in a calm, professional setting. With a focus on safety, visible results and accessibility, the team uses only US FDA and HSA-approved technology, applies a holistic view to beauty and wellness, and avoids hard-selling or pressure tactics.

Open from 11 am daily (until 8 pm Mon-Fri; 6 pm Sat/Sun) and conveniently situated within walking distance of two MRT stations

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