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Losing weight can be a challenging journey, and for many people, the usual approach of diet control and exercise is not enough to achieve significant long-term results. Medical weight loss solutions, particularly weight loss injections, offer a scientifically backed approach for individuals who struggle with obesity or weight-related health issues such as diabetes and hypertension.
Let’s explore some of Singapore's most effective weight loss injections, including Semaglutide, Ozempic, Wegovy, and Mounjaro, and get a more comprehensive guide on their use, benefits, and risks.
Medical weight loss refers to treatments and weight loss interventions supervised by healthcare professionals in a medical clinic. Unlike over-the-counter supplements, slimming centres or trendy diet plans, medical weight loss uses evidence-based prescription medications to achieve safe and sustainable weight reduction under the supervision of a medical professional.
Medical weight loss programmes adopt a holistic approach: combining health screening, prescription medications, lifestyle changes, and professional support with a personalised treatment plan. One of the most effective and scientifically backed approaches to medical weight loss is the use of injectable weight loss medications known as GLP-1 Receptor agonists.
Medical weight loss is indicated for patients with obesity (Body mass index above 27 with obesity-related comorbidity)who have not had success with conventional weight loss methods such as lifestyle modifications (diet and exercise). These individuals are at risk of obesity-related conditions, such as diabetes, hypertension, stroke and heart disease.
GLP-1 receptor agonists are a type of medication that has proven effective in managing obesity and type 2 diabetes. These medications simulate the effects of a naturally existing hormone called glucagon-like peptide-1 (GLP-1), which helps regulate blood sugar levels, appetite, and digestion.
GLP-1 is used in weight loss injectable medications in Singapore. The most well-known among them are Ozempic, Wegovy, Semaglutide, and Mounjaro. Each medication has unique properties, but they all work similarly to help patients achieve their weight loss goals.
Originally created for managing type 2 diabetes, Ozempic (semaglutide) has become an increasingly popular off-label option for weight loss due to its appetite-suppressing properties. Semaglutide, the active ingredient in Ozempic and Wegovy, is a GLP-1 receptor agonist(1).
Semaglutide works by targeting GLP-1 receptors in your brain, the same ones that control hunger and fullness. By activating these receptors, it helps users feel less hungry and more satisfied after eating. It also slows down how quickly their stomach empties, so they stay full for longer and don’t feel the need to snack as often. These effects make it easier to eat less without feeling hungry, helping people lose weight in a more manageable way.
Furthermore, Ozempic helps regulate blood sugar levels while promoting gradual and sustainable weight loss. It is administered once weekly, usually in the abdomen, thigh, or upper arm. Clinical trials have shown that people using Ozempic for weight loss can achieve reductions of up to 15% in body weight over a year when combined with a healthy diet and exercise(1, 2).
Wegovy (semaglutide) is a higher-dose version of semaglutide injection specifically approved for obesity treatment and weight management. It is designed for individuals with obesity and obesity-related comorbidities Wegovy works similarly to Ozempic by mimicking GLP-1, but its higher dosage makes it more potent in promoting weight loss. Like Ozempic, Wegovy is administered weekly and works best with a healthy lifestyle. Wegovy has received regulatory approval in Singapore for the treatment of obesity. (3)
While Ozempic and Wegovy contain the key ingredient semaglutide, Mounjaro contains Tirzepatide, a dual-action hormone that targets both GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors. This dual mechanism makes Mounjaro unique, as it not only controls appetite but also enhances the body's capacity to regulate blood sugar levels. (4)
Mounjaro (Tirzepatide) is also administered as a weekly injection and has demonstrated good results in trials. Participants often experience greater weight loss compared to semaglutide-based treatments, with up to 18% reductions in body weight. Mounjaro's(Tirzepatide) dual-action approach provides a comprehensive solution for weight management.
Mounjaro is approved in Singapore for the treatment of diabetes and is pending approval for the treatment of obesity. Due to worldwide shortage, supply is expected to become available in mid-2025-2026.
Beyond the challenges of following a physically gruelling exercise program, the emotional toll of losing weight can be immense. Many overweight individuals face societal stigma and a sense of hopelessness after failed attempts at dieting and exercising. This combination of physical barriers and psychological stress creates a discouraging cycle, making sustainable weight loss feel almost unattainable.
Medical weight loss treatments, like Ozempic, Wegovy and Mounjaro, offer a promising alternative to those trapped in this cycle. Here's how these treatments benefit individuals struggling with their health and weight:
For people who have tried countless diets and exercise plans with little success, these medications can significantly reduce body weight, bringing about life-changing improvements, such as enhanced mobility and increased energy levels.
Medical weight loss treatments are transformative for individuals with diabetes or prediabetes. By controlling blood sugar levels and improving insulin sensitivity, they reduce the risk of developing or worsening type 2 diabetes.
Weight loss achieved through these treatments often accompanies a dramatic boost in confidence and mental well-being. Shedding pounds can alleviate the emotional burden of obesity, empowering individuals to feel more in control of their health and future.
For those who already feel overwhelmed by their health challenges, the simplicity of a once-weekly injection is a major advantage. It is a manageable schedule that eliminates the need for daily pills or complex routines, making it easier to stay on track.
The most valuable benefit is the potential for lasting change. When combined with lifestyle adjustments like a healthy diet and regular exercise, these medications help patients lose weight sustainably with minimal rebound effect
Ozempic, Wegovy, and Mounjaro are self-administered under the skin (subcutaneous injection) using a pre-filled pen and disposable single-use needles. The process is simple and easy to learn:
At Bay Aesthetics Clinic, patients are taught proper self-injection techniques and can request medical advice and support while undergoing treatment in person or via teleconsultation.
While weight loss injections are generally well-tolerated, some users may experience these side effects:
Nausea, vomiting, diarrhoea, or constipation are common, especially when starting treatment. Most side effects subside as the body adjusts to the medication.
Mild redness, bruising, swelling, or pain at the injection site may occur.
Headaches and fatigue are common side effects, particularly during the initial phase of treatment. These symptoms typically improve with time
Please discuss your health needs and concerns with your doctor to ensure you receive appropriate treatment.
There are some risks to medical weight loss treatments. These can be reduced or managed by visiting a doctor who is experienced in weight loss treatments.
Rapid weight loss can increase the risk of gallstones, particularly in individuals with a history of gallbladder problems. There have been rare reports of pancreas inflammation linked to gallstones.
People who are also using diabetes medications may experience low blood sugar levels.
In animal studies, GLP-1 medication was associated with medullary thyroid tumours, although no human cases have been reported.
Medical weight loss treatments are generally recommended for individuals with:
However, these treatments are only suitable for some. People with a personal or family history of thyroid cancer, pancreatitis, or certain other medical conditions may not be eligible for treatment. Pregnant or breastfeeding individuals should also avoid these medications.
A healthcare provider can help determine whether Ozempic, Wegovy or Mounjaro are the right options based on your health profile.
Ozempic, Wegovy, and Mounjaro are available through licensed medical clinics and healthcare providers. These medications are prescription-only, and obtaining them from reputable sources such as a licenced medical clinic is the only way to ensure safety and authenticity.
Avoid purchasing these medications from unauthorised sellers or online platforms to lower the risk of tainted counterfeit products.
The cost of weight loss injections in Singapore varies depending on the medication, dosage, and duration of treatment. Prices are estimated as follows:
For those struggling to shed excess weight despite diet and exercise, medical weight loss solutions like Ozempic, Wegovy, Semaglutide, and Mounjaro offer a lifeline. These treatments are designed to help individuals achieve safe and sustainable weight loss while improving overall health.
Bay Aesthetics Clinic and Medispa are licensed to provide weight loss solutions, including Ozempic, Wegovy and Mounjaro. Our experienced medical team in Singapore will support you through every step, from choosing the proper semaglutide injection to monitoring your progress and helping you maintain your results. The experienced doctors at Bay Aesthetics Clinic have treated hundreds of weight loss patients with good outcomes and will recommend a personalised treatment plan for you. In addition, the clinic is equipped with body contouring treatments such as Baysculpt Electromagnetic muscle stimulation and SculpSure Laser Lipolysis
Book a consultation to start your weight loss journey.
Most patients start to notice weight loss within 4–6 weeks, with more significant results becoming apparent after 12 weeks of consistent treatment.
While weight loss injections help regulate appetite and metabolism, combining the treatment with a balanced, healthy diet can improve results. We recommend intermittent fasting (16 hours fast with an 8-hour eating window) with a caloric deficit of 500 kcal per day.
Multiple large-scale clinical trials have shown that the medications are safe for long-term use. There is minimal weight gain after stopping the medications
The amount of weight you can lose with Ozempic varies depending on your starting weight, diet and overall adherence to the treatment plan. Individuals can lose 10-15% of their body weight over a 6-12 month period.
Choosing the proper weight loss injection depends on your health needs, medical history, and weight loss goals. Consult with a doctor to discuss your options, and they will guide you to the best treatment.