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CaHA Collagen Boosting Injection is a biocompatible injectable collagen biostimulator and filler in Singapore produced by Merz Aesthetics. It consists of approximately 30% Calcium Hydroxylapatite (CaHA) microspheres suspended in an aqueous gel carrier made of 70% carboxymethylcellulose. CaHA Collagen Boosting Injection delivers a triple effect of face lifting, contouring, and collagen stimulation.
CaHA Collagen Boosting Injection is used for facial rejuvenation (volume augmentation and contouring of the face), skin quality improvement (face, neck, body), acne scar resurfacing, stretch marks, cellulite and hand rejuvenation.
Before we can understand how CaHA Collagen Boosting Injection works, we must first understand the components of our skin and how ageing impacts them.
The structure of our skin is primarily composed of the extracellular matrix (ECM), which plays a crucial role in maintaining the skin’s structural integrity, elasticity, and overall health. Within the ECM are four significant components, namely:
Fibroblasts are another important skin component. These cells produce collagen, elastin, and other ECM components. They maintain the skin’s integrity and are also responsible for wound healing.

As we age, these vital components are affected—collagen and elastin production reduces, weakening the extracellular matrix, and the skin loses its intrinsic ability to retain moisture. Furthermore, fibroblasts’ ability to repair tissue and respond to injury diminishes, and they are more likely to enter a state of senescence, where they stop dividing and release inflammatory factors, contributing to skin ageing and loss of structural integrity. These changes contribute to a decline in skin elasticity, firmness, and overall vitality.
This is where CaHA Collagen Boosting Injection comes in. It contains key ingredient Calcium hydroxylapatite (CaHA) microspheres in a Carboxymethylcellulose (CMC) gel carrier. Upon injection, CaHA Collagen Boosting Injection works through a dual function—the CMC gel helps to provide immediate volume to the treatment area, while the CaHA microspheres stimulate the body’s natural collagen production, providing structural support and further improving skin elasticity. Furthermore, CaHA Collagen Boosting Injection (+) contains lidocaine for added patient comfort. Its components are biodegradable and metabolised naturally.

CaHA Collagen Boosting Injection is the OG Collagen Biostimulator, with over 20 years of clinical experience, >250 clinical publications and 15 million treatments completed worldwide.
In 2003, CaHA Collagen Boosting Injection received CE Certification, the European Union standard for product safety. In 2006, CaHA Collagen Boosting Injection was approved by the FDA, the American Regulatory Authority. Most recently, CaHA Collagen Boosting Injection was the first facial filler to receive US FDA approval for hand augmentation. CaHA Collagen Boosting Injection® has more than 250 publications and is proven to be safe and effective.
CaHA Collagen Boosting Injection can be used to treat the following:

At Bay Aesthetics Clinic and Medispa, our team is dedicated to ensuring a comfortable experience. Upon arrival, our doctors will conduct a thorough consultation with you, checking your medical history to ensure that you are a suitable candidate for CaHA Collagen Boosting Injection.
Next, a bespoke treatment plan will be created, and financial counselling, photo-taking, and consent-taking will be conducted. Next, your skin will be cleansed, and a topical anaesthetic will be applied to minimise discomfort. CaHA Collagen Boosting Injection is then carefully injected using a needle or cannula into the treatment area.
After the treatment, you will see immediate volume restoration and smoothing of wrinkles following your CaHA Collagen Boosting Injection treatment. As collagen production increases, the skin will continue to improve in texture and firmness over the following months. Bear in mind that individual results may vary, but most clients experience a youthful and refreshed appearance that lasts.
Mild redness and swelling may occur for one to two days after treatment, but you can continue to apply makeup and return to normal activity the next day.
Results are visible immediately, with full results in 1-2 months after new collagen has been formed. Results last for 12-18 months, and annual touch-ups are recommended.
Side effects of CaHA Collagen Boosting Injection are rare, with multiple published clinical studies concluding that CaHA Collagen Boosting Injection is safe.
However, some common adverse events include bruising, discomfort, and swelling. Rare adverse events include nodule or granuloma formation, infection, vascular occlusion, and allergy.

Juvederm, Restylane and Belotero are hyaluronic acid (HA) dermal fillers that restore volume and smooth skin. HA fillers can be used in areas with thinner skin and can be dissolved by hyaluronidase. HA fillers are recommended for treating delicate areas such as the lips or undereye, especially for a client wishing to dissolve the fillers in the future. However, HA fillers lack the longevity of CaHA Collagen Boosting Injection and do not stimulate collagen in the skin- making CaHA Collagen Boosting Injection the product of choice for clients seeking long-lasting rejuvenation.
CaHA Collagen Boosting Injection, Sculptra, and Ellanse are Collagen Biostimulators with long track records and good clinical outcomes. For a detailed discussion of their various merits, read this blog post here.
At Bay Aesthetic Clinic and Medispa, a 1.5ml syringe of CaHA Collagen Boosting Injection costs $1500 + GST.
Depending on your treatment areas and goals, the required syringes are typically customised.
This depends on the doctor’s treatment plan; usually, 1 or 2 sessions are recommended.
CaHA Collagen Boosting Injection typically lasts between 12 to 18 months for most patients, although individual results may vary based on several factors. The longevity of CaHA Collagen Boosting Injection's effects can depend on the patient's age, skin condition, treatment area, and lifestyle choices.

With over 10 years of experience in aesthetic treatments, Dr Hoe Ying Min serves as the Medical Director at Bay Aesthetics Clinic. She has extensive hands-on experience in lasers, injectables, body-shaping and skin-rejuvenation procedures, and is known for her careful, personalised approach that aims for natural-looking outcomes.

Bay Aesthetics Clinic and Medispa is a doctor-led clinic located in the Marina Bay Financial Centre that delivers medical aesthetics and medispa treatments in a calm, professional setting. With a focus on safety, visible results and accessibility, the team uses only US FDA and HSA-approved technology, applies a holistic view to beauty and wellness, and avoids hard-selling or pressure tactics.
Open from 11 am daily (until 8 pm Mon-Fri; 6 pm Sat/Sun) and conveniently situated within walking distance of two MRT stations